HerpeSelect® Tests
Ask for it by Name
HerpeSelect is the brand name of the diagnostic test kits manufactured by Focus Diagnostics. HerpeSelect tests utilize highly purified preparations of the HSV type-specific antigens glycoprotein G1 and glycoprotein G2. These antigens are used to detect HSV type-specific antibodies.
HerpeSelect assays are designed to aid in the diagnosis of:
- Sexually active adults, with or without symptoms, who could transmit the virus to a sexual partner.
- Expectant mothers, to reduce the risk acquiring an infection near labor and transmitting the infection during labor.
The selection of assay options on the HerpeSelect product menu makes it easy for a physician or laboratory to provide testing that is right for them and their patients.
Serology tests provide additional information necessary to diagnosis a typespecific HSV infection.
Serology can aid in diagnosis when:
- Culture results are negative
- No symptoms are present but patient states that previous symptoms may have been undiagnosed herpes
Type-specific serology tests provide physicians with the information they need to establish treatment options and provide appropriate patient counseling.
- Type-specific serology can differentiate HSV-1 from HSV-2. Both HSV -1 and HSV-2 can cause genital herpes infection.
- During pregnancy, type-specific serology can identify women at risk of acquiring genital HSV-1 or HSV-2 infections close to labor.
- Treatment recommendations may vary based upon type-specificity as outbreak frequency is often higher with HSV-2 genital infections than with HSV-1 infections.
- Patient counseling may vary based upon type-specificity:
- prognosis and status of sexual health
- risk of transmission to partner
- risk of acquiring genital herpes during pregnancy/transmission to baby
- behavior modification
The HerpeSelect® tests from Focus Diagnostics are available in four formats for detecting type-specific HSV IgG antibodies.1. HerpeSelect® Immunoblot – blot test for detecting HSV-1 or HSV-2.
2. HerpeSelect® ELISA consists of two micro-plate assays, one for detecting antibodies to HSV-1 (gG1), and the other for antibodies to HSV-2 (gG2).
3. Plexus™ HerpeSelect® provides both HSV-1 and HSV-2 from a single specimen using Luminex®xMAP® technology.
4. HerpeSelect® Express™ rapid HSV-2, a point-of-care device providing an HSV-2 serology result from a finger stick in about 15 minutes. (pending CLIA waiver).
Availability
Many laboratories offer HerpeSelect assays for type-specific testing, however others offer the test under a more generic methodology name such as HSV-1 IgG or HSV-2 IgG ELISA. To make it easy, Quest Diagnostics OB/GYN clients have the HerpeSelect name on the laboratory requisition form. Be sure to contact your laboratory to ensure they utilize an FDA-cleared glycoprotein-G based assay.
HerpeSelect Express HSV-2 Rapid Test is now available through Focus Diagnostics for use in CLIA moderately complex sites. CLIA moderately complex laboratories can contact Focus Diagnostics for a distributor in their area.
You can contact Focus Diagnostics online at www.focusdx.com.
Diagnostic Use in the United States
HerpeSelect HSV type-specific serology tests for both HSV-1 and HSV-2 are for in vitro diagnostic use for both sexually active adults and expectant mothers.
HerpeSelect Express is for in vitro diagnostic use in CLIA moderately complex laboratories and is pending CLIA waived status.
HerpeSelect Immunoblot is for in vitro diagnostic use in CLIA moderately complex laboratories.
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