Links
& References
The following websites and support materials are provided
as a convenient resource only and should not be considered a
complete list. The information contained in these websites
is neither endorsed nor controlled by Focus Diagnostics.
Websites
American Herpes Foundation
www.herpes-foundation.org
The website of the American Herpes foundation (AHF), a non-profit
organization committed to improving the management and prevention
of herpes virus infections through research and education. The
site contains both patient and physician information. The site
is supported by educational grants from GlaxoSmithKline and Merck.
American Social Health Association
(ASHA)
www.ashastd.org/hrc
This website for the American Social Health Association (ASHA),
a non-profit organization dedicated to stopping sexually transmitted
diseases and their harmful consequences to individuals, families,
and community. The site provides information about support groups,
the range of hotlines operated by ASHA, and STD news.
For more information, send a self-addressed, stamped envelope to:
National Herpes Resources Center
American Social Health Association
P.O. Box 1327
Research Triangle Park, NC 27709
Herpes Hotline
(919) 361-8488
Centers for Disease Control and Prevention:
http://www.cdc.gov/std/Herpes/STDFact-Herpes.htm
The facts about herpes as presented by The Centers for Disease
Control and Prevention (CDC), the recognized lead federal agency
for protecting the health and safety of people at home and abroad.
Herpes Diagnosis
www.herpesdiagnosis.com
This website was designed by Drs. Lawrence Corey, Rhoda Ashley
and Gray Davis. These 3 individuals have spent over 25 years
working in the field of genital herpes and have been instrumental
in the development of antiviral therapy for the disease as well
as developing the current western blot and PCR based assays for
diagnosing this infection.
International Herpes Management Forum
(IHMF)
www.ihmf.com
The website for the International Herpes Management Forum (IHMF).
The site provides information that can be downloaded and educational
guidelines for doctors and patients on the management of herpes
virus infection. The site offers global links on herpes management,
listing of meetings, and a library of posters and slide presentations
on herpes.
International Herpes Alliances
www.herpesalliance.org
The website for the International Herpes Alliance (IHA), a newly
formed organization that aims to offer support and information
to those with genital herpes, those helping to manage the disease,
and national patient support groups worldwide. A non-profit association
run by patients, medical professionals and support group leaders.
Sponsored by educational grant from GlaxoSmithKline.
Novartis/FAMVIR
www.healthandhope.com
www.famvir.com
www.genitalherpes.com
A website of genital herpes resources information. Includes
a game to tests herpes knowledge along with treatment information.
GlaxoSmithKline/VALTREX
www.herpeshelp.com
www.valtrex.com
www.gsk.com
Facts about genital herpes, cold sores, and varicella zoster
virus. Sponsored by GlaxoSmithKline.
HealthCheck USA
www.healthcheckusa.com
Developed to assist in the prevention of disease by offering
health screening services to the public. HealthCheck USA provides
health awareness screening to customers throughout the USA by
providing patients with direct access to testing services from
the country's major fully accredited medical reference laboratories.
Booklets
"Four Tough Questions about Genital Herpes in the US" from
American Social Health Association, 2000
"A Clinicians Guide to Diagnosis and Treatment of Genital
Herpes" from AMA, November 2002 (funded by GlaxoSmithKline)
"Genital Herpes" authored by Hunter Handsfield, MD,
2001, McGraw-Hill
"You May Think You Don’t See Herpes, but…You
May Only see the Tip of the Iceberg", 2001 (funded by GlaxoSmithKline)
FDA Consumer Magazine, "Genital Herpes: A Hidden Epidemic",
March-April 2002
Scientific Papers
Inaccuracy of Certain Commercial Enzyme Immunoassays in Diagnosing
Genital Infections With Herpes Simplex Virus Types 1 or 2”,
by Rhoda Ashley Morrow, American Journal of Clinical Pathology,
Vol. 120, No.6 (December 2003)
"Sorting Out the New HSV Type-Specific Antibody Tests",
by Dr. Rhoda Ashley, PhD, Sexually Transmitted Infections, Vol.
77, p. 232-237( August 2001)
"Evaluation of Enzyme Immunoassay System for Measuring Herpes
Simplex virus type-1 and type-2 Type Specific IgG Antibodies" by
Harry Prince, PhD, Journal of Clinical Laboratory Analysis 14:13-16
(2000)
“Time Course of Seroconversion by HerpeSelect ELISA After
Acquisiton of Genital Herpes Simplex Virus type-1 (HSV-1) or HSV-2,
by Rhoda Ashley-Morrow, Sexually Transmitted Diseases, Vol. 30
No.4 pp 310-314 (April 2003)
"Reactivation of Genital Herpes Simplex Virus type-2 Infection
in Asymptomatic Seropositive Persons", by Anna Wald, MD, New
England Journal of Medicine, Vol. 342, Number 12; 844-850 (March
2000)
"Risk of Human Immunodefiency Virus Infection in Herpes Simplex
Virus type-2 Seropositive Persons-A Meta Analysis", by Anna
Wald, MD, The Journal of Infectious Diseases, 185: 45-52 (2002)
“Once-Daily Valacyclovir to Reduce the Risk of Transmission
of Genital Herpes”, by Lawrence Corey,The New England Journal
of Medicine, Vol. 350,No.1, pp 11-20 (Jan 2004)
"Underdiagnosis of Genital Herpes by Current Clinical and Viral-Isolation
Procedures", by Laura A. Koutsky, PhD, The New England Journal
of Medicine (1992)
Additonal Scientific References for Herpes Simplex
Virus
Index
of Herpes Simplex Virus Scientific Literature References |
Title |
Primary Author |
Publication / Congress |
Pub. Date |
HerpeSelect Reference |
Development of Clinically Recognizable Genital Lesions
among Women Previously Identified as Having "Asymptomatic" Herpes
Simplex Virus type-2 Infection |
A. Langenberg |
American College of Physicians |
1989 |
|
Strategies for the Prevention of Neonatal Infection with
Herpes Simplex Virus: A Decision Analysis |
M. D. Libman |
Reviews of Infectious Diseases |
1991 |
|
Underdiagnosis of Genital Herpes by Current Clinical
and Viral-Isolation Procedures |
Koutsky |
The New England Journal of Medicine |
1992 |
|
Highly Sensitive Enhanced Chemiluminescence Immunodetection
Method for Herpes Simplex Virus type-2 Western Immunoblot |
J. Dalessio |
Journal of Clinical Microbiology |
1992 |
|
Recurrence Rates in Genital Herpes after Symptomatic
First-Episode Infection |
J. Benedetti |
American College of Physicians |
1994 |
|
Type-specific Antibodies to HSV-1 and -2: Review of Methodology |
R. Ashley |
Herpes |
1998 |
X |
Genital Herpes - How Much of a Public Health Problem? |
Mindel |
Sexually Transmittted Diseases |
1998 |
X |
Improving the Management of Perinatal HSV Infection |
S. Kroon
RJ Whitley |
IHMF - Poster |
1998 |
|
Herpes Management and Prophylaxis |
Barton |
Sexually Transmittted Diseases |
1998 |
|
Herpes Simplex Virus Infection in Pregnancy |
J. Malkin |
Herpes |
1999 |
|
Whole Cell Lysate Enzyme Immunoassays vs. Recombinant
Glycoprotein G2-Based Immunoassays for HSV-2 Seroprevalence Studies |
P. Garcia-Corbeira |
Journal of Medical Virology |
1999 |
|
Ability of a Rapid Serology Test to Detect Seroconversion
to Herpes Simplex Virus type-2 Glycoprotein G Soon after Infection |
Ashley |
Journal of Clinical Microbiology |
1999 |
|
Evaluation of Three Glycoprotein G2-Based Enzyme Immunoassays
for Detection of Antibodies to Herpes Simplex Virus type-2 in Human Sera |
Eis-Hubinger |
Journal of Clinical Microbiology |
1999 |
|
The Place of Serology in Diagnosis of Atypical Genital
Herpes Simplex Virus Infections |
Patels |
8th EADV |
1999 |
|
Genital Herpes: Review of the Epidemic and Potential
Use of Type-Specific Serology |
R. Ashley |
Clinical Microbiology Reviews |
1999 |
|
Herpes Simplex Virus type-1 and type-2 seroprevalence
among pregnant women in the Netherlands |
MA Gaytant |
European Society of Clinical Virology |
2000 |
X |
Evaluation of an Enzyme Immunoassay System for Measuring
Herpes Simplex Virus (HSV) type-1-Specific and HSV-2-Specific IgG
Antibodies |
H. Prince |
Journal of Clinical Laboratory Analysis |
2000 |
X |
Age-Specific Herpes Simplex Virus type-2 Seroprevalence
in General Populations from North, Central and South America |
NJ Robinson |
ICID |
2000 |
|
Herpes Serology for Dermatologists |
Goldman |
Arch Dermatology |
2000 |
X |
Herpes Simplex Virus type-2 Seroconversion Among Persons
Seeking Voluntary Repeat HIV Testing, San Francisco, 1997-1999 |
Turner |
|
2000 |
X |
Reactivation of Genital Herpes Simplex Virus type-2 Infection
in Asymptomatic Seropositive Persons |
Wald |
The New England Journal of Medicine |
2000 |
|
HSV-2 is a major risk factor for HIV infection among
young women in Carletonville (South Africa) |
B. Auvert |
AIDS Congress, Durban 2000 |
2000 |
X |
Genital Herpes and Public Health - Addressing a Global
Problem |
Corey & Handsfield |
JAMA |
2000 |
|
The incidence of Neonatal Herpes in The Netherlands |
M. Gaytant |
International Journal Medical Microbiology |
2000 |
X |
Risk of Human Immunodeficiency Virus Infection in Herpes
Simplex Virus type-2-Seropositive Persons: A Meta-analysis |
Wald |
The Journal of Infection Diseases |
2000 |
|
Population-based herpes simplex virus seroprevalence
in seven countries |
Jen Smith |
International Journal of STD & AIDS |
2001 |
X |
Serological HSV-2 associated with HIV acquisition/transmission
in discordant couples and the general population: Rakai, Uganda |
Gray |
International Journal of STD & AIDS |
2001 |
X |
Use of a Glycoprotein G-Based Type-Specific Assay to
Detect Antibodies to Herpes Simplex Virus type-2 Among Persons Attending
Sexual Transmitted Disease Clinics |
Whittington |
Sexually Transmittted Diseases |
2001 |
|
Multi-Centre Herpes Simplex Virus (HSV) Seroepidemiology
Study |
French |
|
2001 |
X |
Sorting out the new HSV type-specific antibody tests |
Ashley |
Sex Transm Inf |
2001 |
X |
Comparitive Performance of Herpes Simplex Virus type-2-Specific Serological Assays from Meridian and MRL Diagnostics |
Ribes |
Journal of Clinical Microbiology |
2001 |
|
Effect of Condoms in Reducing the Transmission of Herpes
Simplex Virus type-2 from Men to Women |
Wald |
JAMA |
2001 |
|
Performance and Use of HSV Type Specific Serology Test
Kits |
Ashley |
Herpes |
2002 |
X |
Detection of Herpes Simplex Virus type-2-Specific Immunoglobulin
G Antibodies in African Sera by Using Recombinant gG2, Western Blot,
and gG2 Inhibition |
Hogrefe |
Journal of Clinical Microbiology |
2002 |
X |
Efficiency of Reconstitution in Immunoglobulin G from
Blood Specimens Dried on Filter paper and Utility in Herpes Simplex Virus
Type-Specific Serology Screening |
Hogrefe |
Clinical and Diagnostic Laboratory Immunology |
2002 |
X |
Serological Testing for Herpes Simplex Virus (HSV) and
HSV-2 Infection |
Wald |
CID |
2002 |
X |
HSV-2 Antibody Detection in African Sera - Comparison
Between rgG2 ELISA and Western Blot |
Hogrefe |
ESCV |
2002 |
X |
HSV-2 Antibody Detection in African Sera - Investigation
of the Discordance between Recombinant gG2 (rgG2) ELISA and Western Blot |
Hogrefe |
ESCV |
2002 |
X |
Age-Specific Prevalence of Infection Herpes Virus Types
2 and 1: A Global Review |
Jen Smith |
The Journal of Infection Diseases |
2002 |
|
A sero-epidemiological study of herpes virus type-1
and 2 infection in Israel |
Isacsohn |
Journal of Clinical Virology |
2002 |
X |
Evaluation of Confirmatory Strategies for the Detection
of Type-Specific Antibodies against Herpes Simplex Virus type-2 |
Eing |
Journal of Clinical Microbiology |
2002 |
|
Performance of Two Commercial Glycoprotein G-Based Enzyme
Immunoassays for Detecting Antibodies to Herpes Simplex Viruses 1 and
2 in Children and Young Adolescents |
Leach |
Clincial and Diagnostic Laboratory Immunology |
2002 |
X |
Prevalence of Herpes Simplex Virus type-2 Antibody in
Cameroun |
Eis-Hubinger |
Sexually Transmittted Diseases |
2002 |
|
The role of Serological screening in the management of
genital herpes |
Ballard |
MedScover - Infectious Diseases |
2002 |
|
Seroprevalence and Correlates of Herpes Simplex Virus
type-2 Infection in Five Sexually Transmitted-Disease Clinics |
Gottlieb |
The Journal of Infection Diseases |
2002 |
|
Antibodies to HSV-1/HSV-2 in CSF in HSV-2 PCR positive
patients |
Koskiniemi |
Scotland Virology Meeting |
2002 |
X |
The Changing Epidemiology of HSV-1 and HSV-2: Implications
for serological Testing |
Lafferty |
IHMF |
2002 |
|
A Prospective Study of Genital Herpes Simplex type-2
Infection in Human Immuno Deficiency Virus type-1 (HIV-1) - Seropositvie
Women: Correlations with CD4 Cell Count and Plasma HIV-1 RNA Level |
Wright |
CID |
2003 |
|
Strategies for the Prevention of Neonatal Infection with
Herpes Simplex Virus: A Decision Analysis |
Libman |
Reviews of Infectious Diseases |
1991 |
|
The Acquisition of Herpes Simplex Virus During Pregnancy |
Z. Brown |
The New England Journal of Medicine |
1997 |
|
Herpes Simplex Virus type-2 - A Persistent Problem |
A. Arvin, M.D. |
The New England Journal of Medicine |
1997 |
|
Board 126. Evaluation of 2 HSV Type-specific EIA Kits
in Initial and Recurrent Genital Herpes by HSV-1 And HSV-2 |
K.P. Chan |
Abstract presented at ICEID |
2000 |
X |
Evaluation of four commercial enzyme immunoassays for
the detection of type-specific antibodies to herpes simplex virus types
1 and 2 |
Nordbo |
ESCV |
2000 |
|
Potential Benefits of a Serodiagnostic Test for Herpes
Simplex Virus type-1 (HSV-1) to Prevent Neonatal HSV-1 Infection |
Lipsitch |
Sexually Transmittted Diseases |
2001 |
|
HSV-1 and HSV-2 Seroprevalence Study in Estonia |
Kibur |
IHMF |
2001 |
X |
Evaluation of a fully automated glycoprotein G2 based
assay for the detection of HSV-2 specific IgG antibodies in serum and
plasma |
Groen |
Journal of Clinical Virology |
2002 |
|
Time Course of Seroconversion by HerpeSelect ELISA After
Acquisition of Genital Herpes Simplex Virus type-1 (HSV-1) or HSV-2 |
Ashley-Morrow |
Sexually Transmittted Diseases |
2003 |
X |
Effect of Serological Status and Cesarean Delivery on
Transmission Rates of Herpes Simplex Virus From Mother to Infant |
Brown |
JAMA |
2003 |
|
Herpes simplex virus seroprevelance and risk factors
in women |
Smith |
IHMF - Poster |
2003 |
X |
Longitudal Reliability of Focus Glycoprotein G-based
Type-Specific Enzyme Immunoassays for Detection of Herpes Simplex Virus
Types 1 and 2 in Women |
Cherpes |
Journal of Clinical Microbiology |
2003 |
X |
Neonatal HSV Infection: Time to Reconsider the Diagnostic
Approach |
Geretti |
IHMF |
2003 |
X |
Epidemiology of Herpes Simplex type-1 and 2 in Switzerland
: A population-based study |
Bunzli |
IHMF - Poster |
2003 |
X |
HSV-2 remains the predominant cause of genital herpes
among STD attendees in South London: Results of a real-time PCR-based
surveillance study |
Geretti |
IHMF - Poster |
2003 |
X |
Comparative performance of plasma and sera with a herpes
simplex virus type-2 glycoprotein G2-based enzyme immunoassay (HerpeSelect
2 ELISA) |
Cherpes |
IHMF - Poster |
2003 |
X |
Prevalence and acquisition of herpes simplex type-1 infections
in women |
Cherpes |
IHMF - Poster |
2003 |
X |
Diagnosis: Infections and the Nature of the Disease |
Ashley-Morrow |
The Female Patient Supplement |
2003 |
X |
Genital Herpes: Impact on Sexual Health |
Baker |
The Female Patient Supplement |
2003 |
|
Herpes Simplex, The Silent Epidemic |
Steben |
Eurogin Abstract |
2003 |
X |
Performance of Gull and MRL HSV-2 IgG ELISA's for the
detection of Herpes Simplex Virus type-2 Serum Antibodies |
Van Dyck |
Institute of Tropical Medicine - Antwerp |
|
|
| Inaccuracy of Certain Commercial Enzyme Immunoassays in Diagnosing
Genital Infections With Herpes Simplex Virus Types 1 or 2 |
Ashley-Morrow |
American Journal of Clinical Pathology |
2003 |
X |
| Once-Daily Valacyclovir to Reduce the Risk of Transmission
of Genital Herpes |
Corey |
New England Journal of Medicine |
2004 |
|
References
1. Flemming DT, McQuillan GM, Johnson RE, et al. Herpes simplex virus type-2 in the United States, 1976 to 1994. N Engl J Med. 1997;337:1105-1111.
2. CDC. Sexually Transmitted Diseases Treatment Guidelines 2006. MMWR 2006; 55(No.RR-11); 16-21
3. Mertz et al, Ann Internal Med 1992: 116:197-202.
4. Mertz GJ et al. Transmission of genital herpes in couples with one symptomatic and one asymptomatic partner: a prospective study. J Infect Dis. 1988 Jun;157(6):1169-77.
5. Gupta, Warren, Wald et al, The Lancet 2007; 370: 2127-37
6. Corey, L. Clinical Tools for Preventing Transmission of Genital Herpes. Medscape Infectious Diseases 6(1) 2004
7. Freeman EE, Weiss HA, Glynn JR, et al. Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies. AIDS. 2006; 20: 73-83.
8. S.L. Gottlieb et al. Seroprevalance and Correlates of Herpes Simplex Virus Type 2 Infection in Five Sexually Transmitted-Disease Clinics. Journal of Infectious Disease 2002: 186: 1381-1389.
9. Xu F, Sternberg MR, Kottiri BJ, et al. Trends in herpes simplex virus type 1 and type 2 seroprevalence in the United States. JAMA 2006; 296L 964-973.
10. Page J, Taylor J, Tideman RL, Seifert C, Marks C, Cunningham A, Mindel A, et al. Sex Transm Infect 2003; 79: 276-279.
11. Benedetti J, Corey L, Ashley R, et al. Annals of Internal Medicine 1994; 121: 847-854.
|
