Links & References
The following websites and support materials are provided
as a convenient resource only and should not be considered a
complete list. The information contained in these websites
is neither endorsed nor controlled by Focus Diagnostics.
Websites
American Herpes Foundation
www.herpes-foundation.org
The website of the American Herpes foundation (AHF), a non-profit
organization committed to improving the management and prevention
of herpes virus infections through research and education. The
site contains both patient and physician information. The site
is supported by educational grants from GlaxoSmithKline and Merck.
American Social Health Association
(ASHA)
www.ashastd.org/hrc
This website for the American Social Health Association (ASHA),
a non-profit organization dedicated to stopping sexually transmitted
diseases and their harmful consequences to individuals, families,
and community. The site provides information about support groups,
the range of hotlines operated by ASHA, and STD news.
For more information, send a self-addressed, stamped envelope to:
National Herpes Resources Center
American Social Health Association
P.O. Box 1327
Research Triangle Park, NC 27709
Herpes Hotline
(919) 361-8488
Centers for Disease Control and Prevention:
http://www.cdc.gov/std/Herpes/STDFact-Herpes.htm
The facts about herpes as presented by The Centers for Disease
Control and Prevention (CDC), the recognized lead federal agency
for protecting the health and safety of people at home and abroad.
Herpes Diagnosis
www.herpesdiagnosis.com
This website was designed by Drs. Lawrence Corey, Rhoda Ashley
and Gray Davis. These 3 individuals have spent over 25 years
working in the field of genital herpes and have been instrumental
in the development of antiviral therapy for the disease as well
as developing the current western blot and PCR based assays for
diagnosing this infection.
International Herpes Management
Forum (IHMF)
www.ihmf.com
The website for the International Herpes Management Forum (IHMF).
The site provides information that can be downloaded and educational
guidelines for doctors and patients on the management of herpes
virus infection. The site offers global links on herpes management,
listing of meetings, and a library of posters and slide presentations
on herpes.
International Herpes Alliances
www.herpesalliance.org
The website for the International Herpes Alliance (IHA), a newly
formed organization that aims to offer support and information
to those with genital herpes, those helping to manage the disease,
and national patient support groups worldwide. A non-profit association
run by patients, medical professionals and support group leaders.
Sponsored by educational grant from GlaxoSmithKline.
Novartis/FAMVIR
www.healthandhope.com
www.famvir.com
www.genitalherpes.com
A website of genital herpes resources information. Includes
a game to tests herpes knowledge along with treatment information.
GlaxoSmithKline/VALTREX
www.herpeshelp.com
www.valtrex.com
www.gsk.com
Facts about genital herpes, cold sores, and varicella zoster
virus. Sponsored by GlaxoSmithKline.
HealthCheck USA
www.healthcheckusa.com
Developed to assist in the prevention of disease by offering
health screening services to the public. HealthCheck USA provides
health awareness screening to customers throughout the USA by
providing patients with direct access to testing services from
the country's major fully accredited medical reference laboratories.
Booklets
"Four Tough Questions about Genital Herpes in the US" from
American Social Health Association, 2000
"A Clinicians Guide to Diagnosis and Treatment of Genital
Herpes" from AMA, November 2002 (funded by GlaxoSmithKline)
"Genital Herpes" authored by Hunter Handsfield, MD,
2001, McGraw-Hill
"You May Think You Don’t See Herpes, but…You
May Only see the Tip of the Iceberg", 2001 (funded by GlaxoSmithKline)
FDA Consumer Magazine, "Genital Herpes: A Hidden Epidemic",
March-April 2002
Scientific Papers
Inaccuracy of Certain Commercial Enzyme Immunoassays in Diagnosing
Genital Infections With Herpes Simplex Virus Types 1 or 2”,
by Rhoda Ashley Morrow, American Journal of Clinical Pathology,
Vol. 120, No.6 (December 2003)
"Sorting Out the New HSV Type-Specific Antibody Tests",
by Dr. Rhoda Ashley, PhD, Sexually Transmitted Infections, Vol.
77, p. 232-237( August 2001)
"Evaluation of Enzyme Immunoassay System for Measuring Herpes
Simplex virus type-1 and type-2 Type Specific IgG Antibodies" by
Harry Prince, PhD, Journal of Clinical Laboratory Analysis 14:13-16
(2000)
“Time Course of Seroconversion by HerpeSelect ELISA After
Acquisiton of Genital Herpes Simplex Virus type-1 (HSV-1) or HSV-2,
by Rhoda Ashley-Morrow, Sexually Transmitted Diseases, Vol. 30
No.4 pp 310-314 (April 2003)
"Reactivation of Genital Herpes Simplex Virus type-2 Infection
in Asymptomatic Seropositive Persons", by Anna Wald, MD, New
England Journal of Medicine, Vol. 342, Number 12; 844-850 (March
2000)
"Risk of Human Immunodefiency Virus Infection in Herpes Simplex
Virus type-2 Seropositive Persons-A Meta Analysis", by Anna
Wald, MD, The Journal of Infectious Diseases, 185: 45-52 (2002)
“Once-Daily Valacyclovir to Reduce the Risk of Transmission
of Genital Herpes”, by Lawrence Corey,The New England Journal
of Medicine, Vol. 350,No.1, pp 11-20 (Jan 2004)
"Underdiagnosis of Genital Herpes by Current Clinical and Viral-Isolation
Procedures", by Laura A. Koutsky, PhD, The New England Journal of
Medicine (1992)
Additonal Scientific References
for Herpes Simplex Virus
Index
of Herpes Simplex Virus Scientific Literature References |
Title |
Primary
Author |
Publication
/ Congress |
Pub.
Date |
HerpeSelect
Reference |
Development of Clinically Recognizable
Genital Lesions among Women Previously Identified as
Having "Asymptomatic" Herpes Simplex Virus
type-2 Infection |
A. Langenberg |
American College of Physicians |
1989 |
|
Strategies for the Prevention of Neonatal
Infection with Herpes Simplex Virus: A Decision Analysis |
M. D. Libman |
Reviews of Infectious Diseases |
1991 |
|
Underdiagnosis of Genital Herpes by
Current Clinical and Viral-Isolation Procedures |
Koutsky |
The New England Journal of Medicine |
1992 |
|
Highly Sensitive Enhanced Chemiluminescence
Immunodetection Method for Herpes Simplex Virus type-2 Western Immunoblot |
J. Dalessio |
Journal of Clinical Microbiology |
1992 |
|
Recurrence Rates in Genital Herpes
after Symptomatic First-Episode Infection |
J. Benedetti |
American College of Physicians |
1994 |
|
Type-specific Antibodies to HSV-1 and
-2: Review of Methodology |
R. Ashley |
Herpes |
1998 |
X |
Genital Herpes - How Much of a Public
Health Problem? |
Mindel |
Sexually Transmittted Diseases |
1998 |
X |
Improving the Management of Perinatal
HSV Infection |
S. Kroon
RJ Whitley |
IHMF - Poster |
1998 |
|
Herpes Management and Prophylaxis |
Barton |
Sexually Transmittted Diseases |
1998 |
|
Herpes Simplex Virus Infection in Pregnancy |
J. Malkin |
Herpes |
1999 |
|
Whole Cell Lysate Enzyme Immunoassays
vs. Recombinant Glycoprotein G2-Based Immunoassays
for HSV-2 Seroprevalence Studies |
P. Garcia-Corbeira |
Journal of Medical Virology |
1999 |
|
Ability of a Rapid Serology Test to
Detect Seroconversion to Herpes Simplex Virus type-2 Glycoprotein G Soon after Infection |
Ashley |
Journal of Clinical Microbiology |
1999 |
|
Evaluation of Three Glycoprotein G2-Based
Enzyme Immunoassays for Detection of Antibodies to
Herpes Simplex Virus type-2 in Human Sera |
Eis-Hubinger |
Journal of Clinical Microbiology |
1999 |
|
The Place of Serology in Diagnosis
of Atypical Genital Herpes Simplex Virus Infections |
Patels |
8th EADV |
1999 |
|
Genital Herpes: Review of the Epidemic
and Potential Use of Type-Specific Serology |
R. Ashley |
Clinical Microbiology Reviews |
1999 |
|
Herpes Simplex Virus type-1 and type-2 seroprevalence among pregnant women in the Netherlands |
MA Gaytant |
European Society of Clinical Virology |
2000 |
X |
Evaluation of an Enzyme Immunoassay
System for Measuring Herpes Simplex Virus (HSV) type-1-Specific and HSV-2-Specific IgG Antibodies |
H. Prince |
Journal of Clinical Laboratory Analysis |
2000 |
X |
Age-Specific Herpes Simplex Virus type-2 Seroprevalence in General Populations from North,
Central and South America |
NJ Robinson |
ICID |
2000 |
|
Herpes Serology for Dermatologists |
Goldman |
Arch Dermatology |
2000 |
X |
Herpes Simplex Virus type-2 Seroconversion
Among Persons Seeking Voluntary Repeat HIV Testing,
San Francisco, 1997-1999 |
Turner |
|
2000 |
X |
Reactivation of Genital Herpes Simplex
Virus type-2 Infection in Asymptomatic Seropositive
Persons |
Wald |
The New England Journal of Medicine |
2000 |
|
HSV-2 is a major risk factor for HIV
infection among young women in Carletonville (South
Africa) |
B. Auvert |
AIDS Congress, Durban 2000 |
2000 |
X |
Genital Herpes and Public Health -
Addressing a Global Problem |
Corey & Handsfield |
JAMA |
2000 |
|
The incidence of Neonatal Herpes in
The Netherlands |
M. Gaytant |
International Journal Medical Microbiology |
2000 |
X |
Risk of Human Immunodeficiency Virus
Infection in Herpes Simplex Virus type-2-Seropositive
Persons: A Meta-analysis |
Wald |
The Journal of Infection Diseases |
2000 |
|
Population-based herpes simplex virus
seroprevalence in seven countries |
Jen Smith |
International Journal of STD & AIDS |
2001 |
X |
Serological HSV-2 associated with HIV
acquisition/transmission in discordant couples and
the general population: Rakai, Uganda |
Gray |
International Journal of STD & AIDS |
2001 |
X |
Use of a Glycoprotein G-Based Type-Specific
Assay to Detect Antibodies to Herpes Simplex Virus
type-2 Among Persons Attending Sexual Transmitted Disease
Clinics |
Whittington |
Sexually Transmittted Diseases |
2001 |
|
Multi-Centre Herpes Simplex Virus (HSV)
Seroepidemiology Study |
French |
|
2001 |
X |
Sorting out the new HSV type-specific
antibody tests |
Ashley |
Sex Transm Inf |
2001 |
X |
Comparitive Performance of Herpes Simplex
Virus type-2-Specific Serological Assays from Meridian
and MRL Diagnostics |
Ribes |
Journal of Clinical Microbiology |
2001 |
|
Effect of Condoms in Reducing the Transmission
of Herpes Simplex Virus type-2 from Men to Women |
Wald |
JAMA |
2001 |
|
Performance and Use of HSV Type Specific
Serology Test Kits |
Ashley |
Herpes |
2002 |
X |
Detection of Herpes Simplex Virus type-2-Specific Immunoglobulin G Antibodies in African Sera
by Using Recombinant gG2, Western Blot, and gG2 Inhibition |
Hogrefe |
Journal of Clinical Microbiology |
2002 |
X |
Efficiency of Reconstitution in Immunoglobulin
G from Blood Specimens Dried on Filter paper and Utility
in Herpes Simplex Virus Type-Specific Serology Screening |
Hogrefe |
Clinical and Diagnostic Laboratory
Immunology |
2002 |
X |
Serological Testing for Herpes Simplex
Virus (HSV) and HSV-2 Infection |
Wald |
CID |
2002 |
X |
HSV-2 Antibody Detection in African
Sera - Comparison Between rgG2 ELISA and Western Blot |
Hogrefe |
ESCV |
2002 |
X |
HSV-2 Antibody Detection in African
Sera - Investigation of the Discordance between Recombinant
gG2 (rgG2) ELISA and Western Blot |
Hogrefe |
ESCV |
2002 |
X |
Age-Specific Prevalence of Infection
Herpes Virus Types 2 and 1: A Global Review |
Jen Smith |
The Journal of Infection Diseases |
2002 |
|
A sero-epidemiological study of herpes
virus type-1 and 2 infection in Israel |
Isacsohn |
Journal of Clinical Virology |
2002 |
X |
Evaluation of Confirmatory Strategies
for the Detection of Type-Specific Antibodies against
Herpes Simplex Virus type-2 |
Eing |
Journal of Clinical Microbiology |
2002 |
|
Performance of Two Commercial Glycoprotein
G-Based Enzyme Immunoassays for Detecting Antibodies
to Herpes Simplex Viruses 1 and 2 in Children and Young
Adolescents |
Leach |
Clincial and Diagnostic Laboratory
Immunology |
2002 |
X |
Prevalence of Herpes Simplex Virus
type-2 Antibody in Cameroun |
Eis-Hubinger |
Sexually Transmittted Diseases |
2002 |
|
The role of Serological screening in
the management of genital herpes |
Ballard |
MedScover - Infectious Diseases |
2002 |
|
Seroprevalence and Correlates of Herpes
Simplex Virus type-2 Infection in Five Sexually Transmitted-Disease
Clinics |
Gottlieb |
The Journal of Infection Diseases |
2002 |
|
Antibodies to HSV-1/HSV-2 in CSF in
HSV-2 PCR positive patients |
Koskiniemi |
Scotland Virology Meeting |
2002 |
X |
The Changing Epidemiology of HSV-1
and HSV-2: Implications for serological Testing |
Lafferty |
IHMF |
2002 |
|
A Prospective Study of Genital Herpes
Simplex type-2 Infection in Human Immuno Deficiency
Virus type-1 (HIV-1) - Seropositvie Women: Correlations
with CD4 Cell Count and Plasma HIV-1 RNA Level |
Wright |
CID |
2003 |
|
Strategies for the Prevention of Neonatal
Infection with Herpes Simplex Virus: A Decision Analysis |
Libman |
Reviews of Infectious Diseases |
1991 |
|
The Acquisition of Herpes Simplex Virus
During Pregnancy |
Z. Brown |
The New England Journal of Medicine |
1997 |
|
Herpes Simplex Virus type-2 - A Persistent
Problem |
A. Arvin, M.D. |
The New England Journal of Medicine |
1997 |
|
Board 126. Evaluation of 2 HSV Type-specific
EIA Kits in Initial and Recurrent Genital Herpes by
HSV-1 And HSV-2 |
K.P. Chan |
Abstract presented at ICEID |
2000 |
X |
Evaluation of four commercial enzyme
immunoassays for the detection of type-specific antibodies
to herpes simplex virus types 1 and 2 |
Nordbo |
ESCV |
2000 |
|
Potential Benefits of a Serodiagnostic
Test for Herpes Simplex Virus type-1 (HSV-1) to Prevent
Neonatal HSV-1 Infection |
Lipsitch |
Sexually Transmittted Diseases |
2001 |
|
HSV-1 and HSV-2 Seroprevalence Study
in Estonia |
Kibur |
IHMF |
2001 |
X |
Evaluation of a fully automated glycoprotein G2 based assay for the detection of HSV-2 specific
IgG antibodies in serum and plasma |
Groen |
Journal of Clinical Virology |
2002 |
|
Time Course of Seroconversion by HerpeSelect
ELISA After Acquisition of Genital Herpes Simplex Virus
type-1 (HSV-1) or HSV-2 |
Ashley-Morrow |
Sexually Transmittted Diseases |
2003 |
X |
Effect of Serological Status and Cesarean
Delivery on Transmission Rates of Herpes Simplex Virus
From Mother to Infant |
Brown |
JAMA |
2003 |
|
Herpes simplex virus seroprevelance
and risk factors in women |
Smith |
IHMF - Poster |
2003 |
X |
Longitudal Reliability of Focus Glycoprotein
G-based Type-Specific Enzyme Immunoassays for Detection
of Herpes Simplex Virus Types 1 and 2 in Women |
Cherpes |
Journal of Clinical Microbiology |
2003 |
X |
Neonatal HSV Infection: Time to Reconsider
the Diagnostic Approach |
Geretti |
IHMF |
2003 |
X |
Epidemiology of Herpes Simplex type-1 and 2 in Switzerland : A population-based study |
Bunzli |
IHMF - Poster |
2003 |
X |
HSV-2 remains the predominant cause
of genital herpes among STD attendees in South London:
Results of a real-time PCR-based surveillance study |
Geretti |
IHMF - Poster |
2003 |
X |
Comparative performance of plasma and
sera with a herpes simplex virus type-2 glycoprotein
G2-based enzyme immunoassay (HerpeSelect 2 ELISA) |
Cherpes |
IHMF - Poster |
2003 |
X |
Prevalence and acquisition of herpes
simplex type-1 infections in women |
Cherpes |
IHMF - Poster |
2003 |
X |
Diagnosis: Infections and the Nature
of the Disease |
Ashley-Morrow |
The Female Patient Supplement |
2003 |
X |
Genital Herpes: Impact on Sexual Health |
Baker |
The Female Patient Supplement |
2003 |
|
Herpes Simplex, The Silent Epidemic |
Steben |
Eurogin Abstract |
2003 |
X |
Performance of Gull and MRL HSV-2 IgG
ELISA's for the detection of Herpes Simplex Virus type-2 Serum Antibodies |
Van Dyck |
Institute of Tropical Medicine - Antwerp |
|
|
| Inaccuracy of Certain Commercial Enzyme Immunoassays
in Diagnosing Genital Infections With Herpes Simplex
Virus Types 1 or 2 |
Ashley-Morrow |
American Journal of Clinical Pathology |
2003 |
X |
| Once-Daily Valacyclovir to Reduce the Risk of Transmission
of Genital Herpes |
Corey |
New England Journal of Medicine |
2004 |
|
References 1. Flemming DT, McQuillan GM, Johnson RE, et al. Herpes simplex virus type-2 in the United States, 1976 to 1994. N Engl J Med. 1997;337:1105-1111.
2. CDC. Sexually Transmitted Diseases Treatment Guidelines 2006. MMWR 2006; 55(No.RR-11); 16-21
3. Mertz et al, Ann Internal Med 1992: 116:197-202.
4. Mertz GJ et al. Transmission of genital herpes in couples with one symptomatic and one asymptomatic partner: a prospective study. J Infect Dis. 1988 Jun;157(6):1169-77.
5. Gupta, Warren, Wald et al , The Lancet 2007; 370: 2127-37
6. Corey, L. Clinical Tools for Preventing Transmission of Genital Herpes. Medscape Infectious Diseases 6(1) 2004
7. Freeman EE, Weiss HA, Glynn JR, et al. Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies. AIDS. 2006; 20: 73-83.
8. S.L. Gottlieb et al. Seroprevalance and Correlates of Herpes Simplex Virus Type 2 Infection in Five Sexually Transmitted-Disease Clinics. Journal of Infectious Disease 2002: 186: 1381-1389.
9. Xu F, Sternberg MR, Kottiri BJ, et al. Trends in herpes simplex virus type 1 and type 2 seroprevalence in the United States. JAMA 2006; 296L 964-973.
10. Page J, Taylor J, Tideman RL, Seifert C, Marks C, Cunningham A, Mindel A, et al. Sex Transm Infect 2003; 79: 276-279.
11. Benedetti J, Corey L, Ashley R, et al. Annals of Internal Medicine 1994; 121: 847-854.
|
